Hai udit,
serial eeproms can be easily progammed using 8051.
u just need to send the slave addr, sub addr and data thro ur serial interface module.
for writing u need to configure the eeprom in write mode and for reading u need to configure it in the read mode just by sending 0 or 1 along with the slave addr. sub addr is the location in which u want to read or write the data. along with this u need to generate the start and stops to the serial eeprom.
please look out the datasheet of the eeprom ur using and also the i2c standard from phillips.

good luck
-sathish