This approch will remove all wories about serial clocking and latching

If that is a "worry" then you be in big do-do.

I am shipping >5000 16*32 panels every month the panels are made in Taiwan, but I am driving them, four connected in series, using the above method.

The driving of the panels is a matter of ten or so lines of code, the creation of bitmaps (which will be the same in either case) is another story.

Erik