The real issue is to use modern transcievers, The classic 176 transcievers were prone to popping on interconnect problems. just see here what a modern transciever can handle (quoted from Maxim).

"The MAX3443E fault-protected RS-485/RS-422 transceiver features ±60V protection from signal faults on communication bus lines. The device operates from a 5V supply at data rates up to 10Mbps. True fail-safe inputs guarantee a logic-high receiver output when the receiver inputs are open, shorted, or connected to an idle data line. Short-circuit current limiting and thermal shutdown circuitry protect the driver against excessive power dissipation, and integrated ±15kV ESD protection eliminates costly external protection devices."